Abnormal blood test without any physical symptoms.

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My daughter is at age 13 yrs and 9 months,.As a routine blood test ,it was noted that amylase is 137.2 H U/L ,WBC 11.0H x 1000/UL,lymophytes 4,3 H x 1000/UL. LDL is 3.71 mmol/L and ALP is 183.4 U/L . All other tests are within normal limits .She has dermatitis on her legs since last 7 years. It is see always which sometimes become prominent and regresses once the betnovite -N skin cream. kindly let me know what could be the reason for the above results.Please let me advise the treatment which could be given to my daughter.

Submitted: 4 Days
Category: Community

Expert:  Dr. John Monheit replied 4 Days.

Hello,

It seems like your daughter is suffering from an auto immune disorder of multiple sites.

This kind of blood picture is usually seen in an autoimmune disorder. Also considering her age and sex it seems more likely. Autoimmune diseases require a battery of test before being confirmed.

Increased ALP and LDL points towards a liver abnormality whereas increased ALP points towards a biliary system defect. Increased amylase is a classical sign of pancreatic abnormality. Skin rashes also very commonly occur in autoimmune diseases.

Autoimmune diseases are a group of conditions that usually start among young girls .There are a few genes that make it more likely in a few people more than the others. In this condition the cells meant for our protection, instead of acting on foreign cells like bacteria start attacking our own body cells.

I would recommend the following-

1)Consult a GP and discuss with him the possibility of autoimmune disease. There are a few simple tests for screening this disease. The physician might send a blood test for anti-nuclear antibody which is usually is high in all the autoimmune diseases.

2)If it is confirmed that she has a form autoimmune disease she will have to be started on low dose steroids and will need lifelong steroids.

Consult your physician to rule out other common conditions like infection and biliary tract disease.

Thank you.

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