BILIRUBIN level 74 with METASTATIC COLON CANCER.

Hello,
Thank you for your query at DoctorSpring.com
I am one of the InHouse Physicians and before I can assign this consult to our oncologist, can you kindly give us more information on the condition of the patient as of now?
What are the symptoms he/she is having? When was it diagnosed?
Feel free to discuss further,
Regards.

Hi diagnosed nov 2013. Surgery march 2014 for bowel tumor removal. All was fine and mets appeared June 2014 . Liver .
irinotecan failed . Mets size increased . Started oxyplatin and raltitrexed . Had 3 rounds but then in hosp as was having fever and chills . Bowel
inflammation seen on ct . In antibiotics iv 2 weeks and fluids .
Stable response seen from this chemo but liver mets grew by 9mm.suddenly bilirubin in shooting up in the last week. Other liver tests are normal .
experieving fatigue as not eaten much 2 weeks in hosp , appetite loss .
ultrasound done - no bile duct blockage . Bilirubin jumping as
12,19,12,31,51,74,85

Hello,
Will you be able to mail the CT SCAN report and the LFT report?
You can mail them to info@doctorspring.com
That will give me a better idea.

Regards,
Dr. Prasad

I don't have report of bloods but bilirubin jumping as stated above and alt and alp normal .
i attach ct report and his cea was dropping too on chemo
.from 80 it wNt to 40. From seeing the ct images the liver met has only grown 9 mm in 3 months , 3 small liver mets have gone an in liver 3 in total.
ct shows inflammed bowel they said he had colitis as both bowels
were severe inflammed but since in hosp
his bilirubin rising . He was on antibiotic as codine .

I am not sure if chemo will be beneficial with high bilirubin levels but you can try with cetuximab or bevacizumab initially (although with risk).
Kindly consult with your oncologists regarding the fact if they can really help you, as we are suggesting therapy only based on reports and your doctors physically see you and take a decision based on your clinical condition.
Regards

Ok . What is causing the high bilirubin ?will this fail the liver or ?

Hello,
The liver mets as well as the inflamed bowel can cause disturbance in the bile excretion leading to high bilirubin levels.
It definitely needs to come down soon.
Regards.