Low body temperature, less appetite with weight loss. Cause.

Resolved question:
I am a 63 year old female. For the past few weeks, my body temperature has been consistently low (around 36 degrees c), I have been feeling tired and with less appetite than usual. As I have been eating less, my body weight has dropped (that is not really a problem as I have always been a bit overweight).

As a couple of weeks ago I also had pains in my neck and one side of my head, my GP diagnosed nerve inflammation. Now the pain is gone, however the psoriasis I have on my head has worsened and is itching a lot. I also got an extremely bad outbreak of herpes, my lip got really swollen and painful overnight.

This morning, I had blood tests done and here are the results that are out of the normal brackets:

MCV 80.7fl
MCH 27.4pg
MPV 12.4fl

Fasting glucose 6.0

Creatinine 104

C-reactive protein 24.84mg/l

LDL cholesterol 3.4 mmol/l

Iron 7.1

eGFR (MDRD) 46.52ml/min//1.73m2

Could you please comment what could be wrong? (In the past, I have had one kidney, uterus and ovaries removed for kidney cancer, I-ve also had a tumor removed from thyroid, but these were years ago and the analysis have been ok so far).

Can you tell me which specialist(s) should I see or which additional analysis would you recommend?

Submitted: 4 Days
Category: Family Physician-GP

Expert:  Dr. Jaydeep Tripathy replied 4 Days.

Hello,
Thank you for your query at DoctorSpring.com
I understand your concern.
I checked all your reports, and your blood parameters are fine, there are minor variations,however nothing alarming.
What is alarming is though the fact that your creatinine is elevated and the eGFR is significantly low. That could partly be because you have one functioning kidney, however the creatinine is significantly high, and i will suggest a follow up with the nephrologist regarding the same. Creatinine is a waste product and if it keeps accumulating in the serum, it will cause a generalized ill feeling. So you need a follow up with him, regarding your creatinine values. Meanwhile keep drinking adequate water, the more water you drink, the more chances of creat getting excreted.
Also your eGFR is high, so the filtration is not adequate in the kidney, again indicating that the metabolites are accumulating. That could be the main reason why you are not feeling well.
Regarding CRP, it is clear that you had inflammatory episode, with flaring up of psoriasis, and the CRP levels go up during any kind of inflammatory condition in the body like lupus, tuberculosis, or psoriasis. You can take an anti inflammatory like Tab. Advil 2 times a day with food, this will reduce the inflammation and gradually the values will com down.
As of now you need to review your reports with a nephrologist, and discuss about the creatinine and eGFR values.
Hope this was helpful,
Please feel free to discuss further,
Regards.

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