Thank you for asking your query at DoctorSpring.
Since you have a history of Bronchial Asthma with previous history of chest infection, I trust your judgement on possible chest congestion and infection.
If the infection is indeed caused by a bacteria (which also has caused laryngitis) Clarithromycin should be effective. Since there is no response to Clarithromycin a viral infection should also be considered. As you might be aware hoarseness of voice is a well-documented symptom of GERD also (in addition to laryngitis). Allow me to list down my recommendations for clarity.
1. If the symptoms are not very troublesome you can continue clarithromycin. You can step up the dose to 500 mg twice daily for 10 days in total. Changing the antibiotic in mid-way might result in emergence of antibiotic resistance, which is better avoided in your case. The usual respiratory bacteria are susceptible to Clarithromycin in general. So it could be that the anti-bacterial effect is just kicking in, or it’s not a bacterial infection at all.
2. If you has to change an antibiotic I recommend a Cephalosporin like Cefixime 200mg twice daily for 7 days rather that Clotrimazole
3. Do take steam inhalation twice a daily . Also warm saline gargle. This is very important in reducing the congestion
4. Also add an anti allergic medication like Cetirizine or Allegra twice a day.
5. You can continue the MDI (inhalers)
6. A PPI - Like Omeprazole or Pantoprazole can be taken just before sleep ( not with food) once a day for GERD. This might surprise you by relieving the hoarseness
7. We do not offer prescriptions, so please take the medication in consult with your Doctor.
Hope this helps
Please feel free to ask followup questions / clarifications