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Decresed ESTRADIOL on succesive tests. Cause?

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I had my blood work done at 4 weeks 3 day pregnant and my levels came back hcg 2306, progesterone 23.4 ( I did not take progesterone supplements) and estrodiol 223. I had my blood work done again 72 hours later, HCG 7783 progesterone 33.4 (I took 200mg of progesterone supplement/day) and estrodiol at 194. Why did my esrodiol decrease? I'm having my blood work done again today but I want to be prepared for the results. Should I expect progestrone and hcg to go down too?

Thank you for your help.

Category: OBGYN

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Category: Infertility Specialist
 25 Doctors Online

Thanks for posting your query at
See, the main thing to be seen in the blood work is the B HCG.
That is rising as it should.
The estradiol and progesterone will marginally fluctuate, do not read much into it.
And once you are 6 weeks, the blood work should stop , and rely on an ultrasound scan to know the viability of the baby.
Right now, the B HCG levels are fine, and that is all that matters.
You should next expect the B HCG levels to further rise, the progesterone and estradiol could vary.
All the best
Please feel free to discuss further.

Dr. Aarti Vazirani
Category: Infertility Specialist
Residency: Obstetrics & Gynecolog, BJMC,Civil hospital, Ahmedabad, 2008
Post Graduate: MS (Obstetrics & Gynecology), B.J. Medical College, Ahmedabad, 2008
Medical School: MBBS, B.J. Medical College, Ahmedabad, 2004
Dr. Aarti Vazirani and 4 other Medical Specialists are ready to help you

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