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Just suffered another acute gout attack in right big toe. The attacks have become more frequent since the first attack two years old patientago. I'm male, 65, not overweight, exercise, and watch what I eat and drink regarding foods (drinks) high in purines. But the attacks continue. What is more disturbing is the gout like pain I'm experiencing in elbow, wrist, and ankle associated with fractures due to a motorcycle accident over 20 years old patientago. Have hypothyroidism (diagnosed approximately 6 years old patientago) and have been taking various doses (150, 100, now 137) of levothyroxine to get under control. Blood creatinine serum level just came back at 1.7 and has been elevating slightly over the last few years.

1. Is gout (high uric acid) a result of hypothyroidism, or kidney function?. Or is kuindney function (causing high creatinine levels) a result of hypothyroidism?

2. Are former open fractures, especially in joints, a prime place for uric crystal deposit?

Category: Endocrinologist

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Category: Diabetologist
 23 Doctors Online

Thank you for your query at
I have noted your history.
I would like to know if you are on a drug to reduce uric acid levels on a long term basis, like Allopurinol. That will really help.
Let me answer each of your questions.
1. No, the degree of renal dysfunction you have cannot cause such a gout. And no,the kidney dysfunction is not due to hypothyroidism.
Renal impairment is common among patients with gout but its not entirely due to gout. It usually reflects the coexistence of other disorders such as hypertension, diabetes mellitus, obesity, atherosclerosis or, in some instances, lead intoxication resulting from use of unbonded whiskey (moonshine). If you have any such co-existing condition, strict control is required.
2. Uric acid crystals are deposited in the joints, and fractures involving the joints may be precipitating the deposition of these crystals.

I hope that answers your questions. Feel free to ask queries.
Thank you.

Dr. J Muthukrishnan
Category: Diabetologist
1. 10th Asia-Pacific Pediatric Endocrine Society  Fellows meeting, Seoul, Korea, Oct 2008
2. Eighth ICMR Course on Genetics and Genetic Counseling – Jul 2008 – SGPGI, Lucknow
3. Annual Certificate Course on Endocrinological Laboratory Techniques at National Institute of Nutrition (ICMR) Hyderabad,India, ( Aug-Sep 2006) 
Fellowship: Endocrinology, Diplomate of National Board, National Academy of Medical Sciences, New Delhi, 2008, Medwin Hospital, Hyderabad
Senior Residency: Diplomate of National Board (General Medicine), National Academy of Medical Sciences, New Delhi, 2002
Residency: MD, General Medicine, 1997-2000, Armed Forces Medical College, 2nd position in University
Medical School: MBBS, Armed Forces Medical College, 1992
Dr. J Muthukrishnan and 4 other Medical Specialists are ready to help you

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