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Late menstrual cycle with negative pregnancy tests.

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I'm a 45-year-old woman, and my menstrual cycle is 8 days late (35 days since last menstrual period), which is unprecedented for me. Pregnancy tests on days 29, 31, 32 and 34 were negative. Could I possibly be pregnant and not yet far enough along for a positive result? I'm debating over whether to schedule an MD appointment or simply wait it out. Other than slightly sore nipples (common for me during PMS), I am not experiencing any other early pregnancy symptoms.

Category: OBGYN

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Category: Infertility Specialist
 22 Doctors Online

Thanks for posting your query at
You have had consistently negative pregnancy tests, so I do not think you could be pregnant.
Such menstrual irregularities are common around 45.
These could be peri menopausal changes, or simply, an irregular period, that happens once in a while.
I would suggest you to wait it out.
Chart your menstrual cycles in the form of a menstrual diary.
If the irregularity persists, have an OB - GYN evaluation to confirm if this is indeed perimenopause or something like endometrial hyperplasia ( thickening of the lining of the uterus ) that can cause irregular and delayed cycles.
Then you should have an internal exam, a Pap smear, a pelvic ultrasound scan and hormone levels to look for perimenopause ( FSH, LH, Serum estradiol ).
Right now, just wait it out, and let me know how it pans out over the course of the next few days.
All the best
Please feel free to discuss further.

Patient replied :

At day 38 since last LMP; home pregnancy test again confirmed negative for pregnancy. Have a local OBGYN appointment set up for June 30.

Get the workup done as outlined, these might be perimenopausal transient hormonal disturbances.
Nothing much to worry about.

Dr. Aarti Vazirani
Category: Infertility Specialist
Residency: Obstetrics & Gynecolog, BJMC,Civil hospital, Ahmedabad, 2008
Post Graduate: MS (Obstetrics & Gynecology), B.J. Medical College, Ahmedabad, 2008
Medical School: MBBS, B.J. Medical College, Ahmedabad, 2004
Dr. Aarti Vazirani and 4 other Medical Specialists are ready to help you

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