Thanks for writing to us with your health concern.
Yes, estrogen can decrease amount of IGF 1 in the body.
Low IGF 1 levels are associated with development of cardiovascular disease, hypertension and diabetes.
This is theoretically possible.
In practice, only high doses over decades of use can lead to such complications.
Most women all over the globe use birth control pills safely, unless you have a pre existing medical condition or history, they are not contra indicated for you.
All the best.
Please feel free to discuss further.