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Tingling of face and legs

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Hi. I am a 29 year old female and have been experiencing tingling sensations in my face, legs, and hands for the past month. I saw a neurologist, who ordered an MRI which was normal. Just recently I have developed burning sensations in my lower right leg.

After doing some researching these seem to be to be hallmark symptoms of MS. I should also add that I was tested for lyme which was negative. I know that 5 percent of people with MS will have normal MRI's.

Are there any possible explanations for these symptoms other than MS? My husband and I just had a bunch of blood work done for fertility issues all of which was good. I feel like if it was something else ( b12 issue, diabetes, ect.) wouldn't it have come up there?

Anyhow I need to know what questions to ask my doctor as I am scheduled for an appointment tomorrow. Any advice which be greatly appreciated!! I am at the point where I can deal with a scary diagnosis but the not knowing is really difficult for me. Thank you so much for your time!

Thank you!!

Category: Neurologist, Medical

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Category: Pediatric Neurologist
 27 Doctors Online


Thank you for posting your query at

These symptoms can occur with multiple sclerosis, but are not specific for MS. Similar symptoms can also occur with other neurological problems, such as peripheral neuropathy due to vitamin B12/D deficiency or diabetes mellitus.

Also, lack of blood flow to brain/spinal cord or nerves due to conditions such as vasculitis or collagen vascular disease could also result in similar symptoms.

If your symptoms persist, then, you would need to go for other investigations such as MRI of spine, nerve conduction studies, and blood tests for anti-nuclear antibody, vitamin B12, vitamin D levels, etc.

I hope it helps. Please get back if you have any follow up queries.

Best wishes,

Dr. Sudhir Kumar MD (Medicine), DM (Neurology)
Senior Consultant Neurologist

Dr. Sudhir Kumar
Category: Pediatric Neurologist
Senior Residency, Fellowship: DM, Neurology, CMC, Vellore, 2001
Junior Residency: MD, Internal Medicine, CMC, Vellore, 1998
Medical School: MBBS, Christian Medical College, Vellore, 1995
Dr. Sudhir Kumar and 4 other Medical Specialists are ready to help you

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