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Treatment for PERINICIOUS ANEMIA with raised MCV.

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Hi I have recently been diagnosed with Pernicious anemia. It was a shock as I didn't have symptoms . I am unsure about the diagnosis as I have read that alcohol can raise MCV levels. .which could have led to my raised MCV. ..I am also a
vegetarian could the diagnosis be wrong ? The doctor also tested for parietal cells and it came back negative. I am hoping this could be solved through diet rather than injections of b 12 for life...I have had the loading doses which have raised my levels from 190 to 2000. I am now eating meat and don't drink alcohol. Many Thanks

Category: Hematologist

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Category: Hematologist
 24 Doctors Online

Being a vegetarian, can cause deficiency of Vit B12 and that can get corrected with a couple of doses of the injection. Animal diet replenishes the levels.
I would advise you to consume healthy diet and exercise regularly.
You can send your current complete report for review. A repeat blood test after 2 months time can give us a better idea when the recovery is complete

Patient replied :

Hi, Thanks for your reply. did you have a look at my blood test results ?

  • Do you think I have pernicious anemia from the MCV levels /b12 ?
  • Could the raised MCV level be due to alcohol consumption?
  • Do you think correct diagnosis will depend on whether my b12 level stay raised over the next few months ?
  • What would be the expected drop from 2000 over 3 months ? I am also now taking a sublingual B12 - 5000 mg

Many Thanks Louise

1. Yes it could be based on your dietary habits. Veggie are deficient in Vit B 12 but your MCV is not grossly changed. However, since your levels are low, supplement is a must.
2. Alcohol causes decreased absorption of various nutrients including B12 and folates.
3. Take regular nutritional and vitamin supplements which are essential for normal well being.

Patient replied :

Ok thanks. From my fbc would you say I need to increase my ferritin gp says they are normal but I have read over 70 is optimum for women. Many Thanks

Basal levels can be normal. However, more nutritional the food is,
better are the chances of faster recovery. I would advise you to
continue healthy food habits and avoid alcohol totally.

Kind regards.

Patient replied :

Ok but could you give me more details based on my blood results please

Your condition is absolutely normal as per blood reports unless you are very symptomatic about vitamin deficiency. I would suggest you to take healthy hygienic and nutritionally balanced food with lots of fruits, vegetables,egg and meat.
Please revert back in case of any queries.

Dr. Prasad Eswaran
Category: Hematologist
Doctorate in Medicine (Fellowship in Oncology), DM,  Madras Medical College & Govt. General Hospital, Chennai, India.

Doctor of Medicine (Residency in Radiation Oncology) , MD, Christian Medical College, Vellore, Tamilnadu, India, 2004-06.

Diploma in Medical Radiology & Therapy (Residency in Radiation Oncology), D.M.R.T, Madras Medical College & Govt. General Hospital, Chennai, India, 2004-06.

Bachelor of Medicine & Bachelor of Surgery - M.B.B.S, Govt. Stanley Medical College & Hospital, Chennai, India, 1998-2004.
Dr. Prasad Eswaran and 4 other Medical Specialists are ready to help you

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