Helped Over 500,000 patients with 98%+ satisfaction.

Connect & Get Personalized 1-to-1 Answers from Expert Doctors

DoctorSpring > Question Home

Enlarged neck lymph nodes for evaluation.

Resolved Question:

Hi doc, Currently i have swollen lymph nodes in neck and arm pits, mouth burning like anything all the time on the lateralside of tongue, apthous mouth ulcers inside both cheeks, lymphadenitis, pain in b/l arm pits and in the scapular region, pectoral other symptoms............such as fever, headache, diarrhea, skin rash..........

ON 11/28/12 HSV 1 Ig G levels are 3.76...............and Hiv icma test was NEGATIVE;

ON 12/07/12 HIV RNA qualitative test was NEGATIVE...........

ON 02/15/13 HSv 1 IG g levels are 3.38 and HIV icma and Hiv rna QUALITATIVE TEST are NEGATIVE;

ON 07/03/13 HSV 1 IG g levels are 4.02 and HIV icma and HIV rna qualitative negative............

ON 01/06/14 HSV 1 IG levels are 3.62 and HIV icma and HIV rna qualitative test negative..........

ON 01/11/14 my CD4:CD8 profile ratio................. I had my CD4 and CD8 counts run:

Absolute CD4 helper: 879 (range 359-1519)
% CD4 Pos. Lymph: 31.4 (range 30-58)
Absolute CD8 suppressor: 1204 *HIGH* (range 109-897)
% CD8 Pos. Lymph: 43.0 *HIGH* (range 12-35)
CD4/CD8 Ratio: 0.73 *LOW* (range 0.92-3.72)
My other STD tests are negative on the following dates respectively 11/28/12, 02/15/13, 07/03/13, 01/06/14...........
Why my Absolute CD8 suppressor cells are high?
Why my % CD8 Pos. Lymph cells are high?
Why my CD4/CD8 Ratio is low?
Plz interpret the results................................i am worried too much................

Category: HIV- AIDS Specialist

Ask Your Own Question

Category: Diabetologist
 30 Doctors Online


Thank you for choosing DoctorSpring.
I understand your concern and will try my best to help you here.

You have negative STD tests and repeated negative HIV test. Your concern is about the CD8 levels. I am not sure why your Doctor ordered for these tests in the first place. If there was a specific indication please let me know. A very important fact you need to understand is (a misconception lot of people have) that CD4 and CD8 Suppressor cells are NOT all about HIV. They are very dynamic functional component in the human body. From change of temperature to a simple viral illness lot of factors can influence their levels.

In you care the Absolute CD8 suppressor levels are high normal. I will not call it abnormal. Without other correlating or supporting lab finding this has not meaning. Infact this means your immune system is working. These cells are supposed to go up and down. Same with Lymphocytosis. The CD4/CD8 ratio is low because of the relatively high CD8 Count.

I would like to know whether you have done baseline blood tests (Complete Count ), Peripheral Smear etc.
Also was the Lymph node enlargement diagnosed by your Doctor ? If so was it evaluated further ?
May I know the indication for CD4 testing. If it was a self ordered test may I know what prompted you ?

Hope this helped
Thank you

Patient replied :

All these are self ordered tests, lymphadentitis, apthous ulcers are diagnosed by the doctor. CD4/CD8 count test was done along with complete blood count......then why I am having these symptoms...........

CD4 and CD8 levels should not be done as a routine as it will not give any useful information. The symptoms seem to be discrete. Aphthous can occur without a cause. You can use a Chlorhexidine containing mouthwash for this. Also take a B complex vitamin.

Lymph Node enlargement is what requires evaluation. If it persisting for more than 2 weeks you need to do a Peripheral Smear examination (a blood test) followed by a course of antibiotics.

Anyway your are HIV negative and need not repeat the tests. The next evaluation should be step by step and it is better done step by step.

Hope this helps
Thank you

Dr. Jaydeep Tripathy
Category: Diabetologist
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Senior Residency in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

Users who read this, also read:

Make informed and better medical decisions.

Join the 500,000 people who found a smarter, quicker way to get Answers, Recommendations & Expert Opinions.

Expert Doctors at fingertips

Recommendation on next step. Second-opinion.Multi-specialty.

Save Time

Average time for answers: 6 hours.

Save Money

$35 for typical specialist consult vs. $120 for a local appointment.

Free Follow-ups

Clarify, ask further questions for free in private conversation.

100% Satisfaction

Money back guarantee for the 1st reply. MEDNET Quality Board.

Start My Consultation



Doctor Spring is a novel online Doctor consultation platform where you can get your medical questions answered by leading Doctors. Just Submit your question and rest assured that you will consult a Doctor easily. Once you submit the question, the Doctor from the concerned specialty will reply within hours. You can always ask more questions or add details with follow-up question options and make it an online doctor chat. You may use this service to consult a specialty or for getting medical second opinion. All paid services come with a MEDNET quality assurance and 100% money back guarantee.

DoctorSpring in news