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Fever, joint pain after taking IRON for low HEMOGLOBIN.

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My sister is 26 year old and has very low haemoglobin. It was around 9-9.5 and we thought of consulting doctor. Around 3 months ago Doctor put her on iron tablets. After few days she developed severe joint pain (knees, shoulders and neck) and they even started swallowing. She also started getting a lot of fever (of the order of 102-103). At the same time doc conducted one blood test and her esr was found elevated. She was then put on calcium tablets. Her joint pain has definitely reduced but since then she has been suffering from frequent fevers (once in around 5 days that too after taking regular medicines). Also, her ESR level reached very high levels(recent result shows 140 mm/lst hr).
The doctor conducted few tests for artheritis but all were negative. Chest X-Ray and Ultrasound (abdomen) too didn't reveal anything. Everything was fine. Apart from elevated ESR (140) and low Hb (8.6), everything was normal in her latest blood report including (WBC, TLC, platelet count, leucocyte count ).
It has been around 1.5 months that these cycles of fever has been going on. A slight increase in pus cells were reported in one of the urine tests but nothing else. I also observed that she gets fever as and when she feels little restless and the fever accompanies with pain in her one of the knees.
We are completely clueless about all these proceedings . Could you please advise regarding this and let us know what probably could be the reason behind this.
Attaching her latest blood report.


Category: Internal Medicine Specialist

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Dr. Deepu Sebin Sebastian is online now

Expert:  Dr. Deepu Sebin Sebastian replied 4 Days.

Thank you for your query at DoctorSpring.com
There is very little information in terms of investigations for suspected connective tissue disorder. It points towards a connective tissue disorder from the history.
I would request you to get Vit B12, Ferritin, serum Iron status, ANA by immunoflourescence, C- Reactive protein levels, ANTI CCP, Rheumatoid Factor, This would be minimum on which we require to build our case.
It takes one working day to get all the reports. In all probability to rule in or out connective tissue disorder would be high on priority.

Dr. Deepu Sebin Sebastian
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MD, Internal Medicine - Stanley Medical School
Medical School - MBBS - Govt. Medical College, Kottyaam

Diagnostic Prediction - Stanford School of Medicine
Received Specialty training in Critical Care, Cardiology, Neurology, Gastroenterology, Nephrology from Stanley Medical College and in Endocrinology, Rheumatology.

Hematology and Geriatrics from Madras Medical College.
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