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My question is whether there would be a an immunostimulatory approach with supplements, prescription or IV to fight a MRSA Prostatitis which isnt being killed of with antibiotics.... see below. I know it sound like a urology questions but it isnt... I have lots of urologic input..... and am wits end on that.

Non traditional symptoms ( nausea, abdomen discomfort, fatigue…. but no enlargement, urinary issues at all) resulted in 6 months of misdiagnosis as GI Issues.

Two day thorough work up at Mayo Clinic resulted in diagnosis 3.0 years ago “Methicillin Resistant Staph Aureus Prostatitis”

Sensitivities cultures showed many IV antibiotics susceptible plus Bactrim and Minocycline.

Over the next 2.5 years , the symptoms would go from very flush to feeling well within a week on Bactrim. Five 4-6 weeks courses were needed and then months of feeling fine.
It seemed that sexual activity without condom would “activate “ infection two weeks later?

Once again....NO BPH ( prostate regular dimensions, no urinary issues at all.) There would be nausea, a little prostate discomfort, projection of pain to front left ( about one inch to left of belly button and two down). Symtpoms worst upon waking. As soon as Bactrim taken all symptoms would go away

Tried minocycline once and it had pretty strong hypothyroid consequences. Primarily very irregular heart beat. I never tried to overcome with extra thyroid supplementation .

Recently Bactrim was bacteriostatic at best. Doesn't seem to work now to "kill" it off.

I once had to take Zithromax for “travelers diarrhea “ while in Europe and prostate symptoms got better. Made me wonder , do I necessarily have the same bug years later.

When I get it I am quite sick and tired, almost like having flu. It seems like my options are running out on letting this bug take over my life... since it makes it difficult to function.

Recently when visiting with a local urologist he said it may be time for a “hail Mary “ pass , a TURP. In visiting with a friend who is a preventative medicine MD he thought that was early and a bit extreme and dangerous.
Recent careful gray and color Doppler ultrasound study reveals a normal size and configuration prostate for my age. There are multiple calcification, more towards the base. There are no abscesses or masses. There is inflammatory evidence at left mid to apex measuring 12 by 7mm which is the likely location of the infection.


Being as I have no BPH , no urinary issues and localized infection along with a 3 year interval I wonder if there would be be anyway to stimulate my immune system to fight the pathogen.... using suppliments , presctiptions or IV treatment.......??

Category: Urologist

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Category: Sexually Transmitted Diseases(STD)Specialist
 29 Doctors Online

Thank you for your query at
This is Dr Goel again.
Talking of immnostimulation, there is drug available by name of OM 89. However in limited trials it has shown effect as good as placebo only.
You can consider shockwave therapy to prostate. It has shown good short term results in few series. However, I don't have used it personally.
I usually put my difficult patients on tadalafil 5 mg along with alpha blocker and it certainly makes them feel much better. This is not FDA approved use of tadalafil; it is usually used for treatment of erectile dysfunction.
Take your call and try any of the three or all three and you never know what works for you.

Feel free to discuss further,

Dr. Rajiv Goel
Category: Sexually Transmitted Diseases(STD)Specialist
MCh(urology) Medical Council of India
Fellow, Laparoscopic urology, Germany
Fellow, Urooncology and Robotic urology, Australia
Felloship - MCH, Urology/Genito-Urinary Surgery, AIIMS, 2004
Residency - MS, Master of Surgery, AIIMS, 2001
Medical School - MBBS, Bachelor of Medicine and Bachelor of Surgery, AIIMS, 1998
Dr. Rajiv Goel and 4 other Medical Specialists are ready to help you

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