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Itchy, pinching, biting sensation in skin without rash.

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45 year old female, I am experiencing itchy, pinching,biting sensation on the skin,but no rash. I have seasonal allergies and take allegra, which helps with post nasal drainage. this has been going on for about 3 weeks, I went to a urgent about two weeks ago, she prescribed medoral, but didn't help, have tried over the counter antihistimes: zytec, claritin, Allegra, zantac, bendaryl, no thing is helping with this problem. I can't tolerate it anymore. please advice me

Category: Dermatologist

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Category: Sexually Transmitted Diseases(STD)Specialist
 31 Doctors Online

Thank you for your query at
Will you be kind enough to mail us an image of the rash?
That will help us make a diagnosis better.
You can mail us at [email protected]

Patient replied :

I don't have any rash on my body, I have medication allergies, vicodin, stadol, keflex, clindamycin, percocet, phenergan,

Thank you for your query at
Is the itchy sensation throughout or at any particular place?

As mentioned by your previous doctor, you seem to be having urticaria.
The medicines that you have taken usually help in treating urticaria. You have already tried medrol( methyl prednisolone), allegra(fexofenadine), zyrtec( cetrizine), benadryl( hydroxyzine) and claritin( loratidine).Now these could have been ineffective if dose was low or combination was not used.
In my patients, I usually start with Tablet levocetrizine 10 mg twice daily and hydoroxyzine 24 mg twice daily. I also advise my patients to apply calamine lotion mixed with beclomethasone or mometasone lotion twice in a day. If these do not give satisfactory result then I add methylprednisolone 16 mg daily for a week then taper it to 8 mg once daily again for a week. Usually the combination of these three medicines work. If patient complaints of sedation with thesr medicines then these medicines could be replaced by claritin or allegra. However I prefer using these medicines when the intensity of itching is reduced. Avoid taking histamine rich food like cheese, fish, sour fermented food, preservative containing food, tomato, spinach, brinjal etc. If you have a pet stay away from it to avoid animal dander. Avoid extreme changes in temperature.
You may follow these suggestions after consulting your doctor.
Hope this helped.
Take care

Dr. Kalpana Pathak
Category: Sexually Transmitted Diseases(STD)Specialist
M.D. from Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak in 2011 with Haryana State Dental & Medical Council
M.B.B.S from MLN medical college allahabad in 2006 with Uttar Pradesh Medical Council
Dr. Kalpana Pathak and 4 other Medical Specialists are ready to help you

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