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I have laryngopharyngeal reflux (aka silent reflux). I don't have the classic symptoms of GERD (I do have occasional heartburn, but very rarely) and the primary symptoms are occasional hoarseness and a "lump" in the throat that doesn't go away.

I take Nexium 40mg, which seems to make at least some difference. The vast majority of the literature revolves around traditional acid reflux and which medications are best. However, given the variation I have, I'm not sure which direction to go - I'd probably continue with the Nexium if given a first choice, but it's expensive.

(1) So given what I have, do you think there is a difference among prescription Nexium, this new Nexium OTC, Prilosec, and Prilosec OTC?

(2) Or am I better off with H2 blockers like Zantac? or some combination?

(3) If I empty the contents Nexium capsule and take with applesauce, would the effect be the same as swallowing the capsule. (my problem is not with swallowing, but with the gelatin in the capsule.)

Category: Gastroenterologist, Medical

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Category: Hepatologist
 30 Doctors Online

Thanks for posting your query at
I am Dr.R.K and I am pleased to assist you.
I went through your post about LPR and your queries about the medications.
Here are the answers to your queries -
1. Nexium OTC, Prilosec OTC and Prilosec all are PPI and have the same effects. You can take any one of these.
2. Zantac gives good relief. But PPI are better. So you can take any one of the above mentioned medications.
3. Yes you can mix the contents of Nexium capsule with applesauce and swallow it.
I hope that answers your question.
Let me know if I can assist you further.

Dr. Ratnakar Kini
Category: Hepatologist
Fellowship - DM - TN Dr.MGR Medical UniversityResidency - TN Dr.MGR Medical University Medical School - Stanely Medical College, TN Dr.MGR Medical University
Dr. Ratnakar Kini and 4 other Medical Specialists are ready to help you

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