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Do Mirtazapine and Bupropion effect sperm health mobility and count

Resolved Question:

do the following drugs effect sperm health, mobility and count, Mirtazapine and Bupropion? it is almost impossible to find any clear information.

thanks

Category: Family Physician-GP

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Category: HIV- AIDS Specialist
 31 Doctors Online

Hello,

Thank you for asking your query at DoctorSpring

There are NO reports or data which shows evidence for decreased sperm count, motility or any sperm analysis parameter in general.

However there are isolated case reports of decreased sperm motility because of the use of Bupropion. (None available for Mirtazapine). These are mostly observational reports and cannot be considered statistically significant.
The two drugs are relatively free from causing sexual dysfunction when compared to other anti – depressants. More over anti-depressants related effects on sperm parameters will reverse once the drug is stopped.
In short, with available information it can be safely assumed that both drugs has got NO significant influence on sperm parameters. However caution is advised , and consult your Doctor before taking the medication.

Hope this helps
Please feel free to ask followup questions.
Thank you


Patient replied :

Thank you for your prompt reply.

Would you advise trying to conceive while on this medication? My partner is taking these.If its advised not to be taking the drugs while trying to conceive, I would be interested to know what the alternative would be as his mental state deteriorates drastically when not taking them.

Thanks


Yes, why not. Male partner taking anti depressants will not affect the baby's health as per available information. The concern is only if the mother is taking the drugs. Since he is well controlled with these medication he can continue these. Anyway do inform your Psychiatrist regarding this.

Hope this helps
Please fee free to ask followup questions / clarifications.

Thank you


Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
Experience: 
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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