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Lymph node lighting up on PET with epithelioid features

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Doctor, my dad had an oval shaped capsule node(Lymph Node) measuring 3x2x2 cm on the right side of the neck.
report of the microscopic exam of the same shows tumour with epithelioid features.
later on a test of immunohistochemistry of the same sample express that the tumor cell has Desmin, Myogenin, SMA & EMA and are immunonegetive for cytokeratin, S100 protein &CD 34.

this Lymph node again emerged on the same part in the body this time measurring 2.2x 1.8 cm after 2 months.
a F-FDG PET-CT SCAN of the whole body done on 03/09/2013 shows an increased FDG uptake (SUV:9.31 max)in the heterogenously enhancing lesion
involving the right sternocleidomastoid.

a bone mero scan done show no harm and is deemed as normal by the concerned doctor.

i want your opinion on this disease and also what neccesary treatment should be done.
i also want to know if there are any precaution and preventation should be taken by the patience in order to control this disease

Category: Oncologist

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Thank you for your consult at My apologies for the delay with the reply.

I have gone through the reports, your father seems to have developed embryonal rhabdomyosarcoma. It is actually a pediatric disease which some times affects adults as well.

In your father's case as the tumor is localized and has not spread anywhere, it can be taken up for surgery. Then can then can be followed up with chemotherapy. Depending on the surgical margins we can plan for local radiation also.

Chemo with VAC - D can be given, if the general condition of the patient is good.

Hope this helps and i have answered all your queries. Please feel free to discuss further.

Dr Vineel Pampati
Consultant Radiation Oncologist

Dr. Vineel Pampati
Category: Oncologist
Residency: MD, Kasturba Medical College,Manipal
Medical School: MBBS, College of Medical Science, Bharathpur.
Dr. Vineel Pampati and 4 other Medical Specialists are ready to help you

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