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Man on cardio and strength straining with high Creatinine and low GFR

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My lab results show a GFR of 55.74 ml/m^2 and my Creatinine level is at 1.65 MG/DL. I am 43, 6'4, 225 lbs, and I work out, both cardio and weight training, at least 4 to 5 days a week. Im no body-builder but I do have a lot of muscle mass. Im not taking any protein supplements, only MegaMen daily multi-vitamins. Should I be alarmed at my GFR or is it likely that my muscle mass could be skewing my test results?

Category: Family Physician-GP

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Category: HIV- AIDS Specialist
 18 Doctors Online


Thank you for asking your query at DoctorSpring.

The GFR here is eGFR (or estimated GFR) which is actually calculated using an equation from the S.Creatinine. So if the creatinine is high the eGFR will be low.
There is no reason to be alarmed, but at same time you cannot ignore it attributing to the weight training. Weight training can cause high levels, but it has to be made sure it is weight training and nothing else.
I would recommend a repeat testing after 4-5 days without any weight training or vitamin supplement . Take a regular diet on these days. If it is still elevated it will need evaluation. (Theoretically it should come down, if normal).
The value should not be evaluated in isolation. I wonder what the indication for the test is. Any symptoms? Or routine ? What about the S.BUN / Urea and Urine Routine examination ?

You may reply as a followup
Hope this helps

Patient replied :

Thank you for your response. Everything youre saying makes perfect sense. Ill do exactly that. Im not having any sort of symptoms that prompted the testing. It was just routine blood lab (changing Life Insurance companies). I dont see anything on my lab results about S.BUN. My Blood Urea Nitrogen was 21.00 MG/DL. My Creatinine was 1.65 MG/DL. Im also seeing a second Creatinine test result on the back of the paperwork stating 266.00 MG/DL with a lab range of 10-300. Obviously this is different than the other one but possibly worth mentioning. Thank you SO much!

Thank you for providing the additional information.

The Blood Urea Nitrogen is also just above normal. (20 mg/dl) is normal. So definitely a repeat testing of RFT (Renal Function tests – S.Creatinine and Blood Urea Nitrogen ) is warranted. Stay well hydrated.

The other Creatinine should be Urinary Creatinine as a part of the micro albuminuria testing. So that is not significant here.

Thank you

Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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