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Red , irritating rashes on back on LAMICTAL for BIPOLAR.

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I am taking a medicine to treat my bipolar called Lamictal. I was warned to be wary of getting rashes while on the medicine as they can be life threatening. I noticed the backs of my knees were red and irritated a week or so ago after shaving and, having had this reaction to shaving the backs of my legs before, ignored it. A few days after that, my dosage was increased from 25 mg to 50. Since then the irritation seems to have spread a bit. It's not bumpy but it's very dry and red and stings a bit. The location of the rash and the lack of bumps seems to be inconsistent with what I've read online about peoples' reactions to this medication, as well as the early stages of any of the serious skin diseases that can potentially result from the medication. I'm not really sure if I should take my medication tonight, if it's serious, if I should go to ER... Help would be appreciated. Attached is a picture of the 'rash' or irritation.

Category: Dermatologist

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Category: Cosmetic and Plastic Surgeon
 23 Doctors Online


Thanks for posting your query at
I can understand your concern.

This seems to be secondary to shaving as you rightly mentioned. It doesn't seem to be a drug reaction. If it were a drug reaction it wouldn't just involve a localized area but would have been more widespread. Involvement of a mucous membrane i.e of the mouth, nose, eyes, genitals or anal area is common. Presence of hives like rash or fluid filled blisters could be present.

I would recommend application of cortisone cream mixed with Mupirocin cream twice a day for a week on the affected area. Also I would recommend you take a tab. Claritin once daily for a week.

In case there is no improvement or there is an increase in the rash I would recommend that you meet your dermatologist.

Please let me know if you have any queries.
Take care

Dr. Kruti Jobanputra Banodkar
Category: Cosmetic and Plastic Surgeon
Diploma in Dermatology - Royal College Of Physicians & Surgeons Of Glasgow, UK , 2010
Residency - DNB, Dermatology -  K.J Somaiya Hospital, Mumbai, 2009
Medical School & Internship - MBBS - Dr. D . Y . Patil Medical College, Mumbai, 2004
Dr. Kruti Jobanputra Banodkar and 4 other Medical Specialists are ready to help you

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