Helped Over 500,000 patients with 98%+ satisfaction.

Connect & Get Personalized 1-to-1 Answers from Expert Doctors

DoctorSpring > Question Home

Negative effects of TESTOSTERONE injection on body.

Resolved Question:

Age 16 years old patientand 9 months I made a big mistake I took one testosterone enanthanate injection 250-500 mg one time and stopped.. I was going to cycle for football to gain strength and speed but changed my mind after reading the side effects of stunted bone growth and shutting down my natural production.. The things that concern me the most are i want to know truthfully will this negatively affect the growth of my penis ? Or fuse growth plates? Please be very honest I'm very worried and a bit obsessed at this point please tell me what would have happened to my body from taking that.. I'm concerned that the girth growth of my penis will be negatively affected am I wrong ? Please help and if I did mess myself up please just tell me the truth.. Thanks ..

Category: Family Physician-GP

Ask Your Own Question

Category: HIV- AIDS Specialist
 22 Doctors Online

Thank you for your query at

I understand your concern.
You took a good decision not to continue on with the Testosterone injections.

One dose of Testosterone Enanthenate, even 500 mg is not going to affect the growth of your penis, definitely not negatively. So please relax and stop worrying about this.
In fact, children on regular Testosterone supplementation tends to cause enlargement of genitalia, not the reverse! So there is no way that shot would have an adverse effect on your penis size, girth or lengthwise.

Prolonged Testosterone supplementation can cause early maturation of bones and fusion of growth plates but this is not likely with a single shot.

Weight loss too is not likely to affect penis size. Penis size is quite variable among individuals and is influenced by their genetic make-up. External factors like weight loss or nutritional status do not really have any influence on this.

However, bone growth can be affected adversely with poor nutrition.

I hope that answers your questions. Feel free to ask queries.

Thank you.

Patient replied :

Thanks but I know when you supplement testosterone it shuts down natural production. With no testosterone there wouldn't be any penis growth.. So your saying that one dose would not supress my natural levels long enough to affect my final penis size?


One dose will not shut down natural testosterone production significantly to cause such changes.
You have failed to take into account that you provided your body with Testosterone in that injection. So your body had an excess of Testosterone from that shot which could have caused above normal levels of Testosterone for 3-5 days. At this time, your body would have stopped producing Testosterone. Following this, the level of Testosterone from that shot would have gradually decreased over the next 3-4 weeks. When its level was reaching the lower levels of normal in the circulation, your body's feedback would have kicked in and your body's Testosterone production would have started. So on the whole, your body would not have had any time with "no Testosterone" as you have imagined.
Only long term exogenous Testorenone blocks the endogenous Testosterone production in the body, not a single shot.
Testicular size may decrease, not penile size, that too if Testosterone administration continues for many years.

I hope that clears your doubt.
Thank you.

Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

Users who read this, also read:

Make informed and better medical decisions.

Join the 500,000 people who found a smarter, quicker way to get Answers, Recommendations & Expert Opinions.

Expert Doctors at fingertips

Recommendation on next step. Second-opinion.Multi-specialty.

Save Time

Average time for answers: 6 hours.

Save Money

$35 for typical specialist consult vs. $120 for a local appointment.

Free Follow-ups

Clarify, ask further questions for free in private conversation.

100% Satisfaction

Money back guarantee for the 1st reply. MEDNET Quality Board.

Start My Consultation



Doctor Spring is a novel online Doctor consultation platform where you can get your medical questions answered by leading Doctors. Just Submit your question and rest assured that you will consult a Doctor easily. Once you submit the question, the Doctor from the concerned specialty will reply within hours. You can always ask more questions or add details with follow-up question options and make it an online doctor chat. You may use this service to consult a specialty or for getting medical second opinion. All paid services come with a MEDNET quality assurance and 100% money back guarantee.

DoctorSpring in news