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Will overuse of PANADOL NIGHT cause LIVER FAILURE?

Resolved Question:

Dear Doctor,
Because i cant sleep well at night , I use panadol night to help me sleep every night. I did some research about the side effect of panadol night, i found that is cause livers failure if i exceed the limit of usage.
I really found this panadol night great and effective for me.
Please give me your advice in this case ?? And what i can do to prevent livers failure?? Is there any replacement medicine ??.

Category: Family Physician-GP

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Category: HIV- AIDS Specialist
 27 Doctors Online

Thank you for your query at
I understand your concern.
The withdrawal effects of Valium occurs on long term use ( in most cases patients using it for 3 months or more experience withdrawal if they stop the drug abruptly ). But it varies from individual to individual as some people have reported withdrawal symptoms after using the drug for 2 weeks.
The only thing that is a matter of concern here is the high dose.
So it won't be right for you to quit the drug straight away.
The dictum is to reduce the dose by 20 % every 3-5 days till it is below 5 mg. So in your case make it 30 mg first since you used 60 mg, then make it 20 mg, then 10 mg, and then after 5 days you stop the drug.
Feel free to discuss further,

Patient replied :

Thanks - I think you have set my mind at rest - I can taper sensibly at home ??

Given that I was unexpectedly offered a much better new job (which I could hardly turn down) with an associated relocation, almost immediately followed by the loss of a dear relative, I hope I won't have to go through such a traumatic time again! Touch wood!!
Many thanks for your advice!
Kindest regards!
Jane Matthews

Hello Jane,
Yes you can definitely taper it gradually in your house itself.
I am sorry for your loss but you seem strong and I am sure you will fight your way out of it.
Wish you a great new year ahead!!

Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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