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Will a particle in ENDOCARDIUM gets ENCAPSULATED?

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Dear Sir.
Thank you very much.
Below is the last query which I really want to know. Pls. explain me with you medical knowlege.
As you already know that what I still really want to know is particle which stuck in the layer of endocardium could move litttle by little every day into myocardium..(nano meter...)
Below is my query..
If particle move very slowly into myocardium by the blood flow, that mean that particle could not be perfectly encapsulated by fibrin or clot or new cells...
That means there is space which virus or etc could get into endocardium... and if this condition is continuing over 1yr... in my point of view, there may be serious infectious or other symptom..
So, it is impossible particle move every day without any symptom or problem...
Am I right?

Category: Infectious Disease Specialist

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Category: HIV- AIDS Specialist
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Hello,
Thank you for your query at DoctorSpring.com
Yes, I understand your logic.
Such a thing has never happened before. Although your logic makes sense, what does not make sense is how a particle can get to the endocardium. Where is the point of entry? If it is a vein in the hand it will stop in the artery there itself. So can you kindly explain how you think it is possible it reaches the heart? I am sure you have some logic behind that too. Once you explain that, I will answer with my knowledge.
Regarding bacteria or viruses, yes they can definitely move into heart layers.
Hope this was helpful,
Regards.


Patient replied :

Dear sir Thank you very much. I don't have knowlede for medication, if you teach me that i could find out what is wrong in my thought. 1. When i push wood golf in the ground, golf tee broken into half and golf tee which stuck in the ground made my finger cut. While cutting, my finger skin and vein got cut altogether and i could saw the very little vein in finger and blood also came out fron vein. Actually I dont know the vein circulation, so if wood particle enter while cut the vein in finger I thought It could reach the heart. But what I still confused is when i see the finger vein, there are alot of beanch and curve in the finger vein. so if 3mm particle managed to get into finger vein it could be stucked at the point of finger tip. So pls. Teach me that what is wrong in my thought.. 2. Second assumption is 0.7mm sharp particle pierce the skin and reach the vein and prick one side of vein and get into and push other side of vein and vein diameter is somewhat get larger because particle push the other side and not directly pierce and wood particle broken and broken part flow thru the vein and other part cut the other side of vein.. Sorry to bother you again.


Hello,
Thank you for your follow-up.
The point I am trying to explain is if a particle enters your vein it will be stopped there because of inflammatory cells blocking it at the point of entry. So it won't reach heart.
Secondly, yes, if the particle is sharp it can cause massive hemorrhage inside warranting immediate medical attention.
Hope this was helpful,
Regards.


Patient replied :

Dear sir. Thank you very much. What I misunderstand is if particle is small and stuck in half, Echo could not find it out. But I thought that eventhough it is small (3-4mm) it is foreign body, so there is fibrin around particle or somthing else would be covered and stucking part or embedded part could be swellowed, so it is impossible to find out the stucking place. If it is still stuck in the layer of endocardium almost 1yr, and also it is moving very little bit into inside of endocardium, echo could surly find out... am I right?


Hello,
If the particle somehow is still moving around, it is difficult to pick up.
But it is impossible for such a particle to just move around. It will act as an embolus.
Regards.


Patient replied :

Thank you very much. Now I almost understand that my logic has some irrational point. First I thought that blood could push particle more and more into endocardium. But it need more power to push particle into deeper inside of endocardium and myocardium. Same push power could not push particle into more. So in normal if particle stuck in the endicardium, it could not be moved into.. so if not particle pierce the endocardium and touch myocardium, it is impossible to push particle little by little. Below is last query for upper logic. When particle stuck in the endocardium, our cells try to cover the around the particle for holding or not to move... What i want to know is... Because of the continuous push by blood flow, our cell lose the tight ness and finally die and allow the blood flow to push particle into deeper endocardium or more. If it is not possible. I am ok. And what is going to happen if particle continuously attack cell and cell die and make hole in endocardium..


Hello,
The particle has no chance to reach the heart, so other points become irrelevant.
Also, if it moves into endocardium, the course can't be predicted as it is a foreign material. It can be held by cells causing pressure symptoms.
Regards.


Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
Experience: 
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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