Thanks for posting your query at DoctorSpring.com
I apologize for the late reply.
I am Dr.R.K and I am pleased to assist you.
Yes, Calprotectin is a marker of inflammation. So raised calprotectin indicates some inflammation is going on.
With a history of bloody diarrhea and stomach cramps, a raised calprotectin points towards colonic inflammation.
With recurrent episodes, inflammatory bowel disease like ulcerative colitis or Crohn's disease should be considered first.
Virtual colonoscopy may miss the findings.
A conventional colonoscopy may be done to look inside and also to take biopsy if any lesions found. The histopathological examination of the biopsy specimen would help to confirm the diagnosis.
Cancer is unlikely and the colonoscopy also would help to confirm there is no cancer.
I hope that answers your question.
Let me know if I can assist you further.